Nursing requires a wide-range knowledge of illness, medications, and technology; however, it is not enough to simply possess these qualities to be a competent effective nurse. Nursing also requires emotional aspects such as caring, nurturing, and compassion. Thus, changes must be made at educational institutions to devote more attention to cultivating caring among nursing students. The purpose of this project was to explore the question, Do nursing students’ perceptions of caring change after completion of A Nursing Student’s Guide to Caring, a course aimed at nurturing the affective domain? This project investigated the value of caring as a productive framework for transforming nursing curriculum to enhance effectiveness and quality of patient care. The goal of this project was to plan, design, implement, and evaluate the effectiveness of a nursing caring curriculum.