Impaired locomotion in individuals with post-stroke hemiplegia is due, in part, to abnormal muscle activation patterns with respect to amplitude and phasing. It can be theorized that interventions that improve muscle activation patterns may decrease disability in persons with hemiplegia following stroke. The purpose of this study was to determine the change in muscle activation patterns of three lower extremity muscles during forward pedaling after 15 minutes of backward pedaling training on a modified ergometer in persons with post-stroke hemiplegia.