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This is a single-subject research study exploring the use of Palin Parent-Child Interaction Therapy with a Spanish-speaking child who stuttered. Both parents participated with their son in the indirect component of the therapy Program. Results indicated no changes in the level of stuttering frequency from baseline to intervention with the father. In contrast, changes seen with the mother reflect that treatment had an impact on the outcome response in this case. The study also adds findings about changes in the parents’ rating of (a) impact of stuttering on the child, (b) stuttering severity and parental concern, and (c) parents’ knowledge and confidence in dealing with stuttering. Individual variations are also discussed. Considerations for the cultural and linguistic adaption and application of an indirect intervention program for preschool children who stutter are proposed.