Resilience-based clinical supervision (RBCS) is a program that reduces occupational stress and burnout symptoms in healthcare professionals. Research has not yet evaluated the program with medical speech-language pathologists (SLPs) or with an online delivery model. This investigation used virtual RBCS to address burnout in medical SLPs during the COVID-19 pandemic. Six medical SLPs participated in this ABA single-subject experimental design. RBCS was held on Zoom during the intervention phase twice a week for eight total sessions. Exercises included brief mindfulness meditations, emotional labeling, and guided reflective discussions on underlying source of stress. An adapted four-question version of the Oldenburg Burnout Inventory (OLBI) collected repeated measures of burnout twice a week across all study phases. Preintervention and postintervention data were collected with full OLBI assessments to further evaluate intervention effects. All participants showed a decrease in burnout at the end of the study, and five experienced statistically significant reductions in burnout due to the intervention. This investigation contributes to the growing body of evidence supporting RBCS for reducing healthcare burnout, offering a means to increase convenience and accessibility through virtual delivery.