Objective: The objective of this investigation was to determine the efficacy of using matrix training to teach generalization of the core word ‘open’, across verbal operants and activities. A 3×3 matrix was used across storybooks, playtime, and discrete trial teaching for mands, tacts, and verbal operants. Three participants, two males and one female, were recruited between the ages of 6-8 and were all functionally non-verbal. All three participants live in the Middle East and were from bilingual homes. Method: The investigation followed a multiple baseline across participants (MBAP) investigation with three participants. The baseline phase was followed by an intervention phase which utilized most to least errorless teaching for the matrix diagonal. The intervention phase was then followed by a generalization probe to see the effects of generalization across the matrix. Results: In analysis of the data, the statistical relevance is not significant. However, a slight increase in independent generalization across the verbal operants occurred across two of the three participants. Conclusion: In conclusion, generalization of core words, across verbal operants using matrix training resulted in minimal generalization across two of three participants. However, one of the participants was not introduced to the intervention due to session attendance. This is a primary limitation in the MBAP investigation. Other limitations identified include, extended duration of the investigation, changes in the baseline stability definition, and effects of challenging behavior. These, as well as other, limitations should be considered in replications of the present investigation.