This project titled “Hybrid Course Design in Leadership and Management” aims for inclusion in an entry-level Masters of Occupational Therapy (OT) program. Conceptual models from education and occupational therapy will be the foundation of the course development including the Knowledge-to-Action model, Community of Inquiry model, Model of Learning and Teaching Activities, and the occupational-based model of Occupational Adaptation. The Occupational Therapy, Practice Framework: Domain and Practice, 3rd Edition, will guide strategies for successful articulation of education as an area of occupation, and inform the content of topics within the course. Accreditation Council for Occupational Therapy Education (ACOTE) standards will determine student leaning outcomes. A hybrid instructional design using at least fifty percent of online methods will incorporate leadership and management topics essential for occupational therapy practitioners. Multiple educational technologies including a learning management system (LMS) and other applications will result in a flipped classroom and the creation of student personal learning environments and a community of inquiry. Evidence from higher education, instructional technology, occupational therapy education, and leadership and management will provide support for the hybird method of teaching students who are “digital natives” in an ever-changing environment of higher education.