This capstone project develops a syllabus for a pediatric synthesis course, applying a case-based instructional method, for integration into the Master’s entry-level Occupational Therapy (MOT) curricula, situated at the final quarter of the students’ didactic education. The syllabus will include complex pediatric cases for students to analyze and promote clinical reasoning (CR), to therefore improve their confidence in preparation for the students’ pediatric fieldwork level II. The five-week course will meet one time per week, for three hours and will be a one-credit, optional course, offered prior to fieldwork II. This course will be designed for students to integrate previous academic and clinical coursework into clinical application, by expanding professional knowledge, developing skills in communication and reflection, and searching evidence based literature within a small group guided inquiry approach. The syllabus will incorporate guidelines from the Accreditation Council for Occupational Therapy Education of the American Occupational Therapy Association, Blueprint for Education, Blooms Taxonomy, and Vision 2025.